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Briefly, mice were anesthetized with isoflurane and the abdominal cavity was exposed using midline laparotomy, the right ureter was isolated and tied off 0.5 cm from the pelvis

MW 2611.83) EC1454 (16.1mg, 1.2eq) was dissolved in degassed (Ar bubbling) 20mM phosphate pH7 buffer (2.0mL) and added dropwise to a stirring solution of EC1661 (8.7mg, l.Oeq) in dry dimethylsulfoxide (2.0mL, Aldrich) at room temperature with Ar bubbling

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L-Carnitine tablets, 1000 mg, featuring pure, tested Carnipure

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